President Bush says the United States is not contemplating building new military bases in Africa.
Mr. Bush also dismissed rumors Wednesday that the new U.S. regional command for Africa - called AFRICOM - will introduce more American troops to the continent.
Mr. Bush, speaking alongside Ghana's President John Kufour in Accra, also said the United States does not view China as a "fierce competitor" in Africa.
Mr. Bush and First Lady Laura Bush arrived in Ghana Tuesday, the fourth stop of a five-nation tour of Africa.
The Bushes visited an international school and a U.S.-funded center that provides job training to Ghanaians.
Earlier Tuesday, the couple visited Rwanda, where they paid tribute to the estimated 800,000 victims of that country's 1994 genocide. Mr. Bush said the killings are a reminder that "evil must be confronted" in the world.
He also called on all nations to increase efforts to end the ethnic killing in Sudan's war-torn Darfur region, which he has described as genocide. He said the United States will spend $100 million to help train and equip African peacekeepers heading to Darfur.
In addition to Rwanda and Ghana, the Bushes have visited Benin and Tanzania. They are scheduled to visit Liberia on Thursday before returning to Washington.
Some information for this report was provided by AFP and Reuters.